TIA1 and amyotrophic lateral sclerosis: Previous immunohistochemical analysis of basophilic inclusions in aytpical ALS patient tissue identified key constituents of stress granules [poly(A)-binding protein, TIA-1, and ribosomal protein S6] but not markers of other biomolecular condensates such as processing bodies or ribonucleoprotein particles (Fujita et al., 2008).