Ezh2 has been experimentally validated as a direct target of miR-137 in mouse neural stem cells (Szulwach et al., 2010), and also in human glioblastoma cells (Sun et al., 2015) and neuroblastoma cells (Ren et al., 2015) by luciferase reporter gene analysis. This evidence concerns the gene EZH2 and glioblastoma.