Constitutively high levels of endothelial HIF‐1α are known to potentiate a number of pathologies, including hypertension 62, 65 and cancer, when HIF‐1α permanence as a result of hypoxia incurs a vicious cycle of angiogenesis and inflammation, with consequences in tumour cell migration and aggressiveness 2, 36. Here, HIF1A is linked to cancer.