In addition, representative TTC-staining slices in Fig. 1a, b showed that infarct area (%) of slices 2 and 3 were significantly larger in GET-1 mice than observed in the Ntg mice at 7 days after stroke (p < 0.01 for slice #2; p < 0.01 for slice #3, Fig. 1a, b). This evidence concerns the gene OPA1 and stroke disorder.