Interestingly, in pSS patients a significant decrease in CXCR3 + CCR9+ Th cells was found in the central memory (CD45RO + CD27+), effector (CD45RO‐CD27‐) and effector memory (CD45RO + CD27−) subsets, but not naïve Th cells (CD45RO‐CD27+; Figure 1C) in addition, decreased frequencies of CCR6‐expressing CCR9 + effector memory Th cells. The gene discussed is CD27; the disease is peeling skin syndrome.