Next we assessed whether mRNA and protein expression of representative chemokines that can attract CXCR3, CCR4, CCR6 and CCR10‐expressing Th cells were expressed by salivary gland tissue, either expressed as mRNA in tissue lysates or protein levels in supernatant of tissue explants.21, 22 We previously reported that mRNA expression of CCL25 was significantly increased in salivary glands of pSS patients as compared to non‐SS patients.12 Increased CXCL10 mRNA expression as previously reported by others 4 was confirmed (Figure 2A). Here, CCR6 is linked to peeling skin syndrome.