ITGAM and infection: The occurrence of CD11b+CD11c+T‐bet+ AMB‐like B cells has been extensively described in mouse models of chronic viral and bacterial infections, and in many cases are shown to be a fully functional B cell subset able to contribute to protection from infection.99, 100, 101 The peak of CD11c+T‐bet+ B‐cell production in the spleen is detected early after Ehrlichia muris peak infection, and these cells persist thereafter in lower numbers but above background levels accompanying the persistent infection.