Impaired pulmonary function and COPD have previously been linked with the development of AF.21 Worse NYHA status and elevated NT‐proBNP reflect advanced stages of disease, previously related to outcome in HFpEF.22 There are two main differences when comparing AF to SR: loss of atrial contraction, also called the booster pump function, and irregular heart rate. This evidence concerns the gene NPPB and atrial fibrillation.