Several reports have described genetic associations of TAP1 and TAP2 polymorphisms with autoimmune/inflammatory diseases including systemic lupus erythematosus [16], hypersensitivity pneumonitis [19], vitiligo [39], Graves’ disease [40], type I diabetes [41], systemic sclerosis [42], and ankylosing spondylitis [43]. Here, TAP2 is linked to systemic sclerosis.