The results suggested that the expression of MT1G in HCC tissues was significantly downregulated compared to the paired non-tumor tissues (Fig. 1a, p = 0.0006, paired t-test), which was consistent with The Cancer Genome Atlas (TCGA) data (Supplementary Fig. S1A, p < 0.0001) and previous reports16–18. Here, MT1G is linked to hepatocellular carcinoma.