Concentrations of PDGF-AA, PDGF-BB, FGF-2, VEGF and M-CSF in whole lung homogenates from patients with PF-ILD of different aetiologies including IPF, systemic sclerosis (SSc) ILD, other CTD-ILD, sarcoidosis and exposure related-ILD were augmented as compared to healthy donor lungs. The gene discussed is FGF2; the disease is systemic sclerosis.