In univariate analysis, anesthetic technique, body mass index, diabetes, previous percutaneous coronary intervention, history of stroke, chronic kidney disease, dialysis, heart failure, arrhythmia, valve disease, aortic disease, preoperative CRP elevation, previous use of beta blocker and clopidogrel, operation risk, emergent operation, operation duration, intraoperative inotropic requirement and red blood cell transfusion were associated with MINS. The gene discussed is CRP; the disease is chronic kidney disease.