Figure 1b shows that IL18 mRNA expression was lower in skin cancer, colon cancer, and lung cancer, however, higher expression was detected in most other types of cancer, including breast cancer, brain cancer, and pancreatic cancer. Collectively, most tumor tissues had higher IL18 mRNA expression than normal tissues; however, interestingly, SKCM had lower expression. This evidence concerns the gene IL18 and colonic neoplasm.