In addition, in MS patients, ALP showed a positive correlation with osteocalcin, CTX, and P1NP (r 0.36, p < 0.01; r 0.44, p < 0.01; and r 0.43, p < 0.01, respectively); P1NP showed a positive correlation with osteocalcin and CTX (r 0.75, p < 0.01 and r 0.74, p < 0.01, respectively); and CTX correlated positively with osteocalcin (r 0.67, p < 0.01). This evidence concerns the gene CYP27A1 and myeloid sarcoma.