Negative correlations for osteocalcin with 1.25(OH)2D, and P1NP with 24.25(OH)2D, were observed in MS patients only (r −0.24, p = 0.02 and r −0.25, p = 0.02, respectively), as were positive correlations of the ratio between total serum 25(OH)D and 24.25(OH)2D with P1NP and CTX (r 0.27, p = 0.01 and r 0.31, p < 0.01, respectively). The gene discussed is CYP27A1; the disease is myeloid sarcoma.