Northern blot analysis detected two CPE transcripts of 2.4 kb and 1.7 kb in size encoding CPE-WT and a 40 kDa N-terminal truncated CPE variant, CPE-ΔN, respectively, in BXPC-3 pancreatic cancer cells, but only the 2.4 kb transcript was detectable in Panc-1, likely due to the low abundance or rapid turnover of the 1.7 kb transcript. Here, CPE is linked to familial pancreatic carcinoma.