In the DEGs of L8h-vs-D8h, the top most represented KEGG categories included influenza A, herpes simplex infection, TNF signaling pathway, measles, NOD-like receptor signaling pathway, cytosolic DNA sensing pathway, cytokine-cytokine receptor interaction, chagas disease (American trypanosomiasis), and rheumatoid arthritis. Here, TNF is linked to rheumatoid arthritis.