Their study attributed the generation of ROS in NIH3T3 fibroblasts, KB cells, B16 murine melanoma cells, and MDA-MB-231 breast adenocarcinoma cells to the poor coordination strength between the InP core and ZnS shell, resulting in an unstable core/shell relationship that left the InP core exposed in some areas [28]. The gene discussed is NPTX1; the disease is melanoma.