STAT3 and pituitary tumor: These CpG sites are located in or near genes for which methylation and expression were previously reported to be correlated in pituitary adenomas, including STAT5A [10], RHOD [6], GALNT9 [9], and RASSF1 [13], as well as genes with previously described aberrant methylation in pituitary tumors, including CDKN1A, TP73 [14], and STAT3 [15].