S100G and Hypoinsulinemia: To confirm the mechanism of CaBP-9k deletion-induced hypoinsulinemia in response to pancreatic beta cell death, tauroursodeoxycholic acid (TUDCA), which is known as an ER stress reducer, was administered to 3-month-old WT, CaBP-9k, 28k, and 9/28k KO mice for 3 months.