Smith et al. co-injected one of four fluorescent transgenes (rag2:GFP, rag2:dsRED, rag2:zsYellow, or rag2:Amcyan) plus rag2:mMyc to create different colored T-ALL in the syngeneic CG1 background [44,45]. This evidence concerns the gene RAG2 and acute lymphoblastic leukemia.