Exposing rats to pyloric-ligation/indomethacin administration (gastric ulcer control group) expressed a significant reduction in GSH and NO contents and SOD activity as it was 2.83 ± 0.34 Pg/g, 2.40 ± 0.26 μmol/g and 1.58 ± 0.17 U/g, respectively, in comparison to 51.98 ± 2.45 Pg/g, 41.63 ± 1.95 μmol/g, and 25.38 ± 1.04 U/g, respectively, for the normal control group and it expressed a significant elevation in MDA content to 30.50 ± 1.22 ng/g, in comparison to 2.75 ± 0.17 ng/g for the normal control group. Here, SOD1 is linked to gastric ulcer.