In addition, Althaea officinalis pretreatment expressed a significant reduction in peptic activity, histamine, and gastrin contents to 67.08%, 48.53%, and 45.27%, respectively, in comparison to the gastric ulcer control group and it expressed a significant reduction in peptic activity to 61.48%, in comparison to the omeprazole (1st standard pretreatment) group. Here, GAST is linked to gastric ulcer.