These include cell cycle regulatory genes such as fos, cyclin D, c-Myc, pim1 and anti-apoptotic genes such as B-cell CLL/Lymphoma-2 (Bcl-2), Bcl-xL, survivin and X-linked inhibitor of apoptosis protein (XIAP) [23]. The gene discussed is XIAP; the disease is B-cell chronic lymphocytic leukemia.