ESR1 and breast cancer: Luminal A/B (estrogen-receptor and/or progesterone-receptor positive and HER2 (human epidermal growth factor receptor 2) negative or positive) and triple negative/basal like (TNBC) (estrogen-receptor, progesterone-receptor and HER2 negative) are the molecular subtypes of breast cancers where the effects of WFA have been extensively studied [64,65].