PADI1 and infection: We found that while Pdi1ΔO-gly restored the virulence defects observed in Δpdi1 cells during infection in a similar manner to the wt allele, the Pdi1ΔN-gly form failed to complement the lack of Pdi1 (Fig 7B) and the Pdi1ΔN,O-gly form partially complemented the loss of Pdi1.