Maybe most interestingly in regard to our data on promotion of prostate cancer cell motility by PIM1 and NFATC1, there were several genes encoding regulators of the cytoskeletal actin network (INF2, FHOD1, ACTN3, CORO1B) and cell adhesion (COL6A2, PXN, ITGA5). Here, ITGA5 is linked to Familial prostate cancer.