Also, the staining reactions were strong in dual-colour indirect immunofluorescence staining of CD3+CD8− IELs (Additional file 3: Figure S1) and in an immunohistochemical panel (CD4, CD8, CD19, CD163, and FOXP3) consisting of markers known to be relevant for the pathogenesis of coeliac disease (Additional file 4: Figure S2). The gene discussed is CD4; the disease is celiac disease.