Epigallocatechin‐3‐gallate (EGCG) inhibited cancer stem cells characteristics through regulating RXRα/miR‐485‐5p axis.36 Du et al37 demonstrated that overexpression miR‐485‐3p suppressed osteosarcoma cell colony formation, growth, sphere formation and migration and inhibited CtBP1 expression. This evidence concerns the gene RXRA and osteosarcoma.