Increasing evidence indicated that miR‐485 has involved in the progression of varied diseases such as oesophageal cancer, glioma, osteosarcoma, hepatocellular carcinoma, osteoarthritis.30, 31, 32, 33 For instance, Chen and workmates found that miR‐485‐5p expression was negatively related with differentiation degree of bone marrow mesenchymal stem cells (BMSCs).34 Ectopic miR‐485‐5p expression suppressed cartilage surface‐related genes and toluidine blue, while promoted tumour necrosis factor and interleukin partly regulating SOX9 expression. Here, SOX9 is linked to carcinoma of esophagus.