NF1 and neoplasm: In this study, using approaches and analyses identical to those we previously used in our NF1 tumour cell studies [30], we found that STX3451 and another potent sulfamoylated non-steroidal compound, STX2895, effectively induced cell death in NF2 deficient cell lines in vitro at concentrations between 0.3 μM and 1 μM.