IDH2 and glioblastoma: Interestingly, pST2 also shared characteristics similar to those of pST1 or GBM, with molecular enrichment for IDH wildtype (49/54, 90.7%, p < 0.01), 1p/19q non-codeletion (53/54, 98.1%, p < 0.01), MGMT promotor unmethylated (29/54, 53.7%, p < 0.01), chromosome 7 gain paired with chromosome 10 loss (37/54, 68.5%, p < 0.01), chromosome 19/20 gain (6/54, 11.1%, p < 0.01) (Table 1 and Fig. 3c).