Single-nucleotide polymorphisms in exonic regions of FGF14 cause spinocerebellar ataxia 27 (SCA27), an autosomal dominant disease associated with complex neuropsychiatric symptoms6–8,12,21,25,26, while intronic SNPs or changes in the expression level of FGF14 have been linked to schizophrenia and other neuropsychiatric disorders4,5,17. The gene discussed is FGF14; the disease is schizophrenia.