Children with asthma were more likely to have allergic sensitisation: SPT positive to at least one of seven whole allergen extracts [2.40 (1.92–3.00)]; and elevated asIgE levels to any of three whole allergen extracts [2.45 (1.53–3.91)], and higher total IgE (Table 3). This evidence concerns the gene IGHE and asthma.