In addition, their results supported the conclusion that the exosome level was associated with the levels of some inflammatory factors, such as C-reactive protein, soluble tumor necrosis factor-α (TNF-α) receptor-1, and interleukin-6 (IL-6), in the plasma, which implied a possible role for exosomes in the inflammatory reactions of COPD. The gene discussed is IL6; the disease is chronic obstructive pulmonary disease.