Our results indicate that the vascular hypoplasia observed in patients with MMD might be caused by IL-10 insufficiency, despite the observed increase in the number of CD206-positive M2 macrophages, which produce and release IL-10 as well as other cytokines and facilitate vasculogenesis19,20 in PBMNCs cultured from patients with MMD. Here, MRC1 is linked to multiminicore myopathy.