Specifically, these studies suggest that higher alanine aminotransferase (ALT)4,5 or aspartate aminotransferase (AST)5 rather than other measures of liver function, such as glutamyltransferase (GGT)4–6, could play a role in T2DM, although one small MR study found no association of ALT with T2DM7. The gene discussed is GPT; the disease is type 2 diabetes mellitus.