Consistent with mRNA levels, BCL-XL protein was strikingly lower in melanoma (Fig. 1g and Supplementary Fig. 2f) compared to CRC, NSCLC and pancreatic lineages (median value of <4 fmol vs. >11 fmol per μg total cellular protein). The gene discussed is BCL2L1; the disease is non-small cell lung carcinoma.