Nevertheless, in Figures 1I–1M, 2K–2O and 2R–2V, and Supplementary Tables 17–26, the TMEM246-AS1, AL133467.3, ZNF582-AS1, LINC01510 and PSMG3-AS1 genes were downregulated in kidney cancer samples and indicated poor prognosis when lowly expressed, which revealed that TMEM246-AS1, AL133467.3, ZNF582-AS1, LINC01510 and PSMG3-AS1 tended to be protective factors with higher gene expression for a Cox HR <1. The gene discussed is PGAP4; the disease is kidney cancer.