AP000439.2 was found to involve renal cell carcinoma, fatty acid, tryptophan, histidine and glycerolipid metabolism, and the mTOR signaling pathway (Supplementary Figure 20C), while AC124854.1 might participate in the adipocytokine signaling pathway, renal cell carcinoma, histidine metabolism, mTOR signaling pathway and glycolysis gluconeogenesis (Supplementary Figure 21A). Here, MTOR is linked to renal cell carcinoma.