We next screened the entire PAH Biobank cohort, including participants of non-European ancestry, for rare deleterious variants in KLK1 and GGCX. In total, 12 cases carried KLK1 variants (10 IPAH, 2 APAH) and 28 cases carried GGCX variants (17 IPAH, 9 APAH, 1 FPAH, 1 unknown subclass) (Table 2). The gene discussed is KLK1; the disease is pulmonary arterial hypertension.