Moreover, it has been suggested that the Oxytocin action in adipocyte differentiation could be mediated by Erk1 / 2 phosphorylation [30] and it would appear that the Oxytocin - FGFR3 / Erk axis plays a key role in the establishment of the phenotype observed in achondroplasia. This evidence concerns the gene FGFR3 and achondroplasia.