SLC1A3 and schizophrenia: Further studies linked loss of EAAT1 in mice to locomotor hyperactivity in a novel environment, to abnormal sociability and to impaired learning, behaviour interpreted as ‘schizophrenia-related’ abnormalities [66,67] and a recent report showed that loss of EAAT1 alters the firing patterns of a subpopulation of cerebellar Purkinje cells and causes discrete neuronal cell loss [68].