Homeostatic model assessment of Insulin Resistance (HOMA-IR), Glucose and Hemoglobin A1c IFCC (International Federation of Clinical Chemistry and Laboratory Medicine unit of measure) were substantially higher in Severe NAFLD subjects as well as glutamate-oxalacetate transaminase (GOT) and glutamate-pyruvate transaminase (GPT), C-Peptide and Insulin. This evidence concerns the gene GPT and Insulin resistance.