In triple negative breast cancer cells (TNBC), Sal-B did not change caspase-3 or caspase-8 suggesting that death-receptor (extrinsic) pathway is not involved in overall apoptotic effect whereas Sal-B inhibited Bcl-xL and survivin expression indicating the involvement of mitochondrial (intrinsic) pathway. This evidence concerns the gene BCL2L1 and triple-negative breast carcinoma.