We do not know whether lower levels of IL-1β, IL-6, IL-8, IL-10, IL-12, IL-13, IL-17A, TNF, and IFN-γ in ZIKV offspring at 32 days (Fig 3C; S1E Table) were caused by subclinical in utero ZIKV infection or maternal cytokine background (S2 Fig). This evidence concerns the gene IL6 and Zika virus infectious disease.