Interestingly, we previously showed that the overexpression of CRT enhanced the expression of RNA binding protein FUBP1, which binds to ARE in 3’ UTR of FUT1 mRNA, and therefore stabilized FUT1 mRNA in J82 bladder cancer cells to promote tumor formation and metastasis [23, 24]. The gene discussed is CALR; the disease is urinary bladder carcinoma.