Consistent with this finding, Ma Y et al demonstrated that miR‐27a serves as an oncogene in various cancers, and its expression had been found to be up‐regulated in PC.23 A recent study concluded that the down‐regulation of miR‐27a results in the inhibition of cell growth and invasion as well as the promotion of apoptosis.24 In addition, BTG2 was verified as the target gene of miR‐27a following the detection of luciferase activity and quantification. Here, BTG2 is linked to pachyonychia congenita.