CACNA1F is a voltage‐gated calcium channel that is mainly expressed in the human retina, but it has also been reported to be widely distributed outside the retina, including in the immune system.58 It is well documented that CACNA1F plays roles in cell proliferation, migration, and apoptosis,59 but it is rarely reported in CRC; therefore, further research on CACNA1F is needed. The gene discussed is CACNA1F; the disease is colorectal carcinoma.