PC‐induced contact dermatitis is thought to be a Th1‐driven immune response, and IFN‐γ produced from T cells is considered to play an important role in the development of dermatitis.32 In addition, we previously reported that LCZ inhibited IFN‐γ production by human peripheral blood mononuclear cells in vitro.19 These observations suggest that LCZ suppresses PC‐induced contact dermatitis in mice by inhibiting IFN‐γ production from T cells that have infiltrated the skin. This evidence concerns the gene IFNG and dermatitis.