Expression data showing downregulation of AMPK regulator PRKAG3 could be indicative of altered glycogen storage, with glycogen storage disease and PRKAG2 (isoform of PRKAG3) mutation seen in some cases of cardiomyopathy (Porto et al. 2016; Banankhah et al. 2018). This evidence concerns the gene PRKAG2 and disorder of glycogen metabolism.