Depletion of TNFAIP8 in prostate cancer cells increases anti-proliferation and apoptosis-related genes such as IL24, FAT3, LPHN2, and EPHA3, fatty-acid oxidation gene, ACDL, and decreases the expression of several oncogenes including NFAT5, MALAT1, MET, FOXA1, KRAS, S100P and OSTF1 [8]. The gene discussed is TNFAIP8; the disease is Familial prostate cancer.