HE4, human epididymis protein 4; PCOS, polycystic ovary syndrome; BMI, body mass index; FGS, Ferriman Gallway Score; LH, luteinizing hormone; HOMA-IR, homeostasis model assessment-insulin resistance; Total-C, total cholesterol; DHEAS, dehydroepiandrostenedion sulfate; Total-T, total testosterone; r, correlation coefficient. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.