Further recurrent genetic lesions in AML relevant for this work include lysine methyl transferase 2A (KMT2A; previously known asMLL) fusion genes, partial tandem duplications withinKMT2A (KMT2A-PTD), and fusion genes between promyelocytic leukemia and retinoic acid receptor alpha (PML-RARA). Here, KMT2A is linked to acute myeloid leukemia.