We also observed an enrichment on genes present at the neuronal synapse such as glutamate (GRM5), cholinergic (CHRNA2) and GABA receptors (GRIN2C, GABRR1, GABRR2 and GABBR2), teneurin (TENM2), calsyntenin (CLSTN3), or the cytoskeletal alpha-actin protein (ACTN2) for the diverse meta-analyses involving ventricular measures and AD. This evidence concerns the gene GABRR1 and Alzheimer disease.